• Introduction Thienopyrimidines comprise a thiophene ring fus

  2018-11-03

  

  Introduction Thienopyrimidines comprise a thiophene ring fused with the pyrimidine moiety similar to the imidazole moiety in purines [1]. Thienopyrimidines in general have become an interesting structural element in development of pharmaceutical compounds [2,3], and have among others been evaluated

• br Conclusion br Acknowledgements We would

  2018-11-03

  

  Conclusion Acknowledgements We would like to thanks the editors and the anonymous referees of the journal for constructive comments and suggestions, which have significantly helped to improve the contents of the paper. Furthermore, special thanks to Fundamental Research Grant Scheme (FRGS) Vot

• During observation to avoid bias from previous

  2018-11-03

  

  During observation, to avoid bias from previous experience in VR operation of the respondents, which could affect the evaluation, the VR camera was set up at an angle of 45° from the ground, thus capturing a fly-through movie (hereinafter \"VR movie\") that circles around from a bird\'s-eye view. Th

• Major nonintubated VATS pulmonary resections such as segment

  2018-11-02

  

  Major nonintubated VATS pulmonary resections, such as segmentectomy or lobectomy, usually require a longer surgical time and intensive hilar manipulation. Therefore, appropriate conscious sedation with amnesia is required for our patients to tolerate the uncomfortable decubitus position for hours in

• br Conclusion RSP can be obtained from the enzymatic hydroly

  2018-11-02

  

  Conclusion RSP can be obtained from the enzymatic hydrolysis of rapeseed protein, and can be fractionated into four fractions with various molecular masses by gel filtration on a Sephadex G-25 column. Fraction RSP-4 revealed the highest ABTS radical-scavenging activity and ACE-inhibiting capacity

• vorapaxar Medicinal plants refer to the class of plants appl

  2018-11-02

  

  Medicinal plants refer to the class of plants applied for therapy or to possess pharmacological actions for human and animal. In morphological aspect, there is no difference between medicinal and others plants, except the characteristics of certain plant to exhibit medicinal benefits. Indonesia comp

• Direct genetic reprogramming of postnatal

  2018-11-02

  

  Direct genetic reprogramming of postnatal primary cells by forced expression of key developmental transcription factors has emerged as an alternative to in vitro differentiation of PSCs. This strategy has been used successfully to produce functional cells, including neurons, hepatocyte-like cells a

• br Materials and methods br

  2018-11-02

  

  Materials and methods Results Discussion It is known that mutation types of SOD1 affect not only enzymatic activity and protein half-life of SOD1, but also age at onset and the survival time of SOD1-ALS patients (Hayward et al., 2002) (Borchelt et al., 1994) (Regal et al., 2006). However, t

• br Experimental Procedures br Acknowledgments br Introductio

  2018-11-02

  

  Experimental Procedures Acknowledgments Introduction Fragile X syndrome (FXS; OMIM #300624) is the most common heritable form of cognitive impairment. It is inherited as an X-linked trait and is caused by a deficiency in the fragile X mental retardation protein (FMRP) (Santoro et al., 2012)

• health-related Introduction Reprogramming somatic cells to i

  2018-11-02

  

  Introduction Reprogramming somatic health-related to induced pluripotent stem cells (iPSCs) holds great promise for disease modeling and therapeutic applications. Among the challenges that remain is the extended time frame and variable efficiency of transcription factor-based reprogramming; in mos

• br Experimental Procedures br Author

  2018-11-02

  

  Experimental Procedures Author Contributions Acknowledgments Introduction The mammary gland is a unique organ because its functional development and differentiation are completed postnatally. Ductal branching and elongation take place during puberty, whereas lobulo-alveolar development a

• Expansion is a canonical white noise

  2018-11-02

  

  Expansion is a canonical white-noise expansion in terms of a wavelet basis, i.e., it is a sum of random quantities multiplied by determinate time-varying functions, in this case, wavelet ones. Amiantov\'s study proved, in particular, the assumption that the probability density functional takes the

• At the IV III phase transition the third

  2018-11-02

  

  At the IV→III phase transition, the third harmonic coefficient γ3ω for nanostructured (as well as for bulk) potassium iodate (Fig. 3b) takes the minimal value, increasing by about four times with further heating. Thus, the temperature studies of the capacitance and the third harmonic coefficient hav

• br Introduction Light emitting diodes LEDs due to

  2018-11-02

  

  Introduction Light emitting diodes (LEDs) due to their technical and economic advantages (low power consumption, a long service life and low service costs, a small size, the absence of hazardous IR and UV radiation, ease of disposal) are the leading contenders for future light sources. Currently,

• br Statistical analyses We estimate one model for each

  2018-11-02

  

  Statistical analyses We estimate one model for each health outcome. For the physical markers of health, as well as self-rated health we estimate model 1, while for the health behaviour outcomes we estimate model 2:where Y is the outcome variable; MAB is the maternal age at the time of birth for t

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